Basic Concepts In Photobiomodulation Photobiomodulation involves the use of light within the visible red (600-700 nm) or near infrared (NIR) (700 nm-1400 m) range that is produced from a laser or light-emitting diode (LED) source. These wavelengths coincide with the “optical window” of mammalian skin, that is, the wavelength at which there is maximal absorption of light. Unlike regular lasers which produce tissue heating or ablation, absorption of light by a chromophore in PBM produces a photochemical effect that is analogous to photosynthesis in plants. Cytochrome C oxidase, a member of the mitochondrial electron transport chain, acts as the chromophore that leads to production of adenosine triphosphate (ATP), generation of reactive oxygen species, and induction of cell signaling.This results in cell proliferation, down-regulation of inflammation, increased tissue oxygenation, wound healing, nerveregeneration, and pain reduction. Principle: Cytochrome…
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